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Thyroid Hormones | Gland | Hypothyroidism | Hyperthyroidism👨‍⚕️

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Thyroid Hormones | Gland | Hypothyroidism | Hyperthyroidism‍⚕

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▬▬▬▬▬▬▬▬▬▬ Contents of this video ▬▬▬▬▬▬▬▬▬▬

00:00:00 Introduction and functions of thyroid hormone
00:01:38 Structure of thyroid gland, follicles, Para follicles and their hormones
00:06:19 What is follicle, its structure and its function
00:12:13 Function of Follicle and steps of formation of thyroid hormones
00:16:24 Function of Iodide Pumps
00:19:43 What is Thyroid peroxidases and its function
00:21:17 Thyroglobulin protein production and its function
00:27:58 Organification of iodide
00:31:30 Coupling reaction in thyroid hormone synthesis
00:39:55 Colloid structure
00:40:40 Recap of Thyroid Peroxidase Functions
00:44:34 Transportation of Thyroid hormones from Colloid to Blood
00:52:28 Thyroid Deiodination enzyme
00:55:05 Recap
01:00:40 Anti thyroid substances (thiocyanate, perchlorate, PTU, carbimazole)
01:11:19 Recap
01:18:20 Wolf Chaikof effect
01:19:20 How T3 & T4 are getting into circulation and then into peripheral tissues
01:27:25 Thyroid Hormones in pregnancy and TBG
01:29:02 How the Secretion of T3 & T4 regulated by pituitary gland; TRH, TSH
01:37:30 How TSH work on thyroid gland
01:48:40 Changes in cells due to overstimulation by TSH
01:51:52 How TSH is regulated, positive & negative feedback mechanism, Temperature and emotions
01:59:30 Low T3 syndrome
02:02:40 Factors which stimulate and inhibit T3 & T4
02:08:25 How Thyroid hormones work on targeted tissues
02:27:02 What are major effects of T3 & T4 on body? Increase transcription of many genes, Increase metabolic activity
02:39:15 Physiological actions of Thyroid hormones, Physical & mental growth and maturation, specific bodily mechanism
03:29:10 Thyroid hormones, glands and its clinical cases
03:30:11 Graves’ disease, Thyrotoxicosis, signs and symptoms
03:42:24 Toxic Thyroid Adenoma
03:45:57 Multinodular Toxic Goiter
03:46:50 Exogenous administration of thyroid
03:47:11 Clinical Features related to Hyperthyroidism and Hypothyroidism
04:06:10 Primary Hyperthyroidism
04:08:88 Pituitary Hyperthyroidism
04:09:30 Hypothalamic Over release of TRH
04:10:19 Basic management of Hyperthyroidism
04:12:41 What is Hypothyroidism & Primary Hypothyroidism? HashimotosThyroiditis, Treatment
04:24:25 Pituitary Hypothyroidism
04:26:51 Hypothalamic Hypothyroidism
04:28:24 Cretinism



Thyroid hormone synthesis includes the following steps: (1) iodide (I) trapped by the thyroid follicular cells; (2) diffusion of iodide to the apex of the cells; (3) transport of iodide into the colloid; (4) oxidation of inorganic iodide to iodine and incorporation of iodine into tyrosine residues within thyroglobulin.

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