In this Double Take video from the New England Journal of Medicine, Sam Telford and Robert Smith provide a clinical overview of the various tickborne diseases commonly encountered across the United States, including Lyme disease, babesiosis, and anaplasmosis, among others. Starting with characteristics of ticks and their ability to act as disease vectors, the video reviews the clinical presentation of these infections, clues on physical examination, and laboratory tests to consider when encountering a patient with a potential tickborne infection.

The New England Journal of Medicine is the world's leading general medical journal. Continuously published for over 200 years, NEJM publishes peerreviewed research along with interactive clinical content for physicians, educators, and the global medical community at https://NEJM.org.