In this video, we discuss medications used as treatment for Major Depressive Disorder and what the recent treatment guidelines suggest as firstline treatments which include secondgeneration antidepressants such as SSRIs, SNRIs, NDRI's, and Multimodal antidepressants. Top medications from each of these classes are discussed including potential side effects.

If you are in a mental health crisis, please dial 988 from the U.S. Or text HOME to 741741 and connect to a crisis counselor.
You can find a list of international crisis lines here: https://blog.opencounseling.com/suici...

Intro 0:00
Considerations 00:33
SSRIs 01:26
SNRIs 05:29
Atypical antidepressants:
Bupropion 08:29
Vortioxetine 09:45
Mirtazapine 10:55
Rare and Dangerous side effects 12:41
Takeaways 16:52

Resources:
Deprescribing Guide: https://amzn.to/4dZEUMk
Stahl's Prescribing Guide: https://amzn.to/3UXj8QL

Disclaimer: All of the information on this channel is for educational purposes and not intended to be specific/personal medical advice, or substituted for diagnosis and treatment of any conditions discussed herein. Furthermore, watching these videos or getting answers to comments/questions, does not establish a providerpatient relationship. Please consult with your own health care provider for proper diagnosis and treatment.

References:
American Psychological Association (APA). (2019). Clinical practice guideline for the treatment of depression across three age cohorts. APA.org. Retrieved from https://www.apa.org/depressionguideline
Bjarnadottir, A. (2018, December 4). A guide to common antidepressant side effects. Healthline. Retrieved from https://www.healthline.com/health/ant...
Hirsch, M., & Birnbaum, R. J. (2019) Sexual dysfunction caused by selective serotonin reuptake inhibitors (SSRIs): Management. Up To Date. Retrieved from https://wwwuptodatecom.libproxy.eku...
Kennedy, S. H., Lam, R. W., McIntyre, R. S., Tourjman, S. V., Bhat, V., Blier, P., Hasnain, M., Jollant, F., Levitt, A. J., MacQueen, G. M., McInerney, S. J., McIntosh, D., Milev, R. V., Müller, D. J., Parikh, S. V., Pearson, N. L., Ravindran, A. V., Uher, R., & CANMAT Depression Work Group (2016). Canadian Network for Mood and Anxiety Treatments (CANMAT) 2016 Clinical guidelines for the management of adults with major depressive disorder: Section 3. Pharmacological treatments. Canadian Journal of Psychiatry, 61(9), 540–560. https://doiorg.libproxy.eku.edu/10.1...
Rush, J.A (2020). Unipolar major depression in adults: Choosing initial treatment. Up to Date. Retrieved from https://wwwuptodatecom.libproxy.eku...
Stahl, S. (2017). Stahl’s essential psychopharmacology: prescribers guide (6th ed.). New York,
N.Y.: Cambridge University Press.

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