Link for Living with Depression Video by Kat Napiorkowska:
   • LIVING WITH DEPRESSION  

What is Treatment Resistant Depression? There is No consensus on a standardized definition of Treatment Resistant Depression.

Common definition “major depressive episodes that do not respond satisfactorily after two trials of antidepressant monotherapy”
Dr. Charles Conway – JAMA 2017 article on lack of consensus “limits the ability to do comparative treatment research, to understand the biological underpinning of TRD, and produces ambiguous medical insurance coverage issues.”

Dr. Philip Wang – APA Director of Research: “Without an agreed upon definition of TRD, different payors may be using different criteria to determine what they will reimburse for… Ideally, you would have a uniform definition so that insurance coverage would be more consistent.”
STAR*D Trial – sequential treatment with antidepressants.