Mark Scholz, MD, is a medical oncologist who specializes exclusively in the management and treatment of men with prostate cancer. Here, he answers patients' questions from our YouTube comments on the relationship between MRIs and biopsies.

0:09 I am 74 years old and have a PSA between 3.9 and 4.2. I had an MRI with a PIRADS 5. Should I get a biopsy or recheck my PSA?

2:42 How does the PIRADS system work?

4:56 Are lowergrade tumors like Gleason 6 usually smaller than highergrade aggressive tumors?

6:38 What is the significance of the number of cores positive, and does it matter where the cores are positive (e.g., anterior vs. posterior parts of the prostate gland)?

7:45 Do tumors tend to grow in certain areas of the prostate gland?

8:52 How often do you suggest second opinions on biopsy reports? Are there certain criteria that would cause you to suggest seeking a second opinion?

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The Prostate Cancer Research Institute (PCRI) is a 501(c)(3) notforprofit organization that is dedicated to helping you research your treatment options. We understand that you have many questions, and we can help you find the answers that are specific to your case. All of our resources are designed by a multidisciplinary team of advocates and expert physicians, for patients. We believe that by educating yourself about the disease, you will have more productive interactions with your medical professionals and receive betterindividualized care. Feel free to explore our website or call our free helpline at 1 (800) 6417274 with any questions that you have. Our Federal Tax ID # is 954617875 and qualifies for maximum charitable gift deductions by individual donors.

The information on the Prostate Cancer Research Institute's YouTube channel is provided with the understanding that the Institute is not engaged in rendering medical advice or recommendation. The information provided in these videos should not replace consultations with qualified health care professionals to meet your individual medical needs.

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