Ornithine transcarbamylase deficiency is the most common enzyme defect in the Urea cycle. This causes hyperammonemia that doesn't present with megaloblastic anemia. There are many amino acid derivatives that give rise to neurotransmitters, hormones, etc. The ones covered here are phenylalanine, tryptophan, histidine, glycine, glutamate, and arginine. This video covers an indepth synthesis of the catecholamines.

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