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Wegovy: Weight Loss Benefits vs. Kidney Health Risks | Dr. Dan | Obesity Expert

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Dr. Dan | Obesity Expert

Understanding Wegovy and Kidneys: Protection or Potential Harm?

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Does Wegovy, also known as semaglutide or Ozempic, help or harm your kidneys? According to some “google doctors” in my comment sections, the answer is a resounding YES! But, hold on—it’s not that simple. If you take a GLP1 based medication like Wegovy and drastically reduce your water intake or experience vomiting and diarrhea, you could become dehydrated, which might harm your kidneys. But it’s not the Wegovy itself causing harm; it’s these rare circumstances that might lead to kidney issues.

On the flip side, exciting new research suggests Wegovy could actually protect your kidneys!

A large, randomized controlled trial, the FLOW Trial, involved 3,500 people with Type 2 Diabetes and CKD. Participants were split into two groups: one received semaglutide, and the other got a placebo, with everyone on the drug for about 3.4 years. The trial aimed to see if semaglutide could reduce the risk of kidney failure, significant kidney function decline, and kidney or heart disease.

The results? Semaglutide reduced the risk of these combined outcomes by 24%. Specifically, it lowered the risk of a major reduction in kidney function by 27% and the risk of dying from heart disease by 29%. It also reduced the risk of dying from any cause by 20% and slowed the yearly decline in kidney function by about 1.16ml/min. These findings suggest that semaglutide has significant protective effects on the kidneys.

Regarding side effects, nothing new emerged from this trial. The standard GLP1 side effects like nausea, heartburn, and constipation were observed. The trial spanned three years, adding to the longterm safety profile of semaglutide.

Overall, this study was welldesigned. Despite the involvement of Novo Nordisk, the trial sponsor, independent consultants verified the data. The results are a win for semaglutide and GLP1 based therapies, showing benefits in reducing risks and protecting kidney function in people with Type 2 Diabetes and CKD.

Thanks for watching and always remember: small tweaks lead to massive peaks!
Dr. Dan


Watch my previous videos about how to fight obesity and about the best medicine for weight loss:

▪ Watch This Before Taking Mounjaro:    • Watch This Before Taking Mounjaro | D...  
▪ From Ozempic to Mounjaro:    • How to Switch from Ozempic (or Wegovy...  
▪ Muscle Loss with Ozempic, Wegovy & Mounjaro:    • Muscle Loss with Ozempic, Wegovy and ...  
▪ Managing Nausea from Ozempic, Wegovy and Trulicity!:    • Managing Nausea from Ozempic, Wegovy ...  
▪ Ozempic: Stomach Paralysis Update:    • Ozempic: Stomach Paralysis Update | D...  
▪ How to Switch from Ozempic (or Wegovy) to Mounjaro:    • How to Switch from Ozempic (or Wegovy...  
▪ Ozempic Paralyzed My Stomach:    • Ozempic Paralyzed My Stomach  
▪ How to Inject Mounjaro: stepbystep tutorial:    • How to Inject Mounjaro: stepbystep ...  


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Disclaimer of Medical Liability. HEALTHCARE EVOLUTION INC. DOES NOT PROVIDE MEDICAL ADVICE. The content of this material is for general informational purposes only. The content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Reliance on any information provided here is solely at your own risk. Individual medical needs are very different; you should not assume that the information in this document concerning certain courses of treatment or outcomes will apply to you. Rather, you should evaluate your medical condition and make treatment decisions based upon consultation with your physician.

#Wegovy #Obesity #KidneyHealth

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