In this Double Take video from the New England Journal of Medicine, Drs. Schubach, Gravallese, and Firestein review the epidemiology, clinical features, pathogenesis, and diagnostic evaluation of rheumatoid arthritis. The video also explores available therapeutic approaches to the disease, including strategies to manage flares.

For further reading, the following Review Article, referenced in the video, is available at NEJM’s website: Rheumatoid Arthritis — Common Origins, Divergent Mechanisms (Gravallese and Firestein, in the February 9, 2023, issue of NEJM; https://www.nejm.org/doi/full/10.1056... ).

The New England Journal of Medicine is the world’s leading general medical journal. Continuously published for over 200 years, NEJM publishes peerreviewed research along with interactive clinical content for physicians, educators, and the global medical community at NEJM.org.

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