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MDS expert Valeria Santini, MD, of the University of Florence, advises patients to ask their doctor which genetic tests are available for suspected myelodysplastic syndromes (MDS). Karyotype testing for chromosomal abnormalities in MDS is essential, as is genetic testing that can find a wide array of mutations, including less common ones. Patients should ask about testing to look for new mutations during and after treatment so treatment can be adjusted if necessary.